Preparation Of Collagen-Sulfonated Carboxymethyl Chitosan/Silicone Membrane Bilayer Dermal Equivalent And Its Application In The Treatment Of Scalds Of Porcine Skin Preparation Of Collagen-Sulfonated Carboxymethyl Chitosan/Silicone Rubber Skin Regeneration Material And Its Comprehensive Treatment On Scalded Wounds Of Mini Pigs Research On The Repair Of Skin Defectsª¬ª³
Keywords
Sulfonated Carboxymethyl Chitosan,Collagen,Dermal Equivalent,Scald,Angiogenesis Sulfonated Carboxymethyl Chitosan,Collagen,Skin Regeneration Material,Scald,Vascularization
Abstract
A dermal equivalent applied in the treatment of scalds has been attracting much attention.We report here the fabrication of a bilayer dermal equivalent(BDE) composed of collagen-sulfonated carboxymethyl chitosan(SCC) porous scaffold and silicone membrane,and its application for accelerating the healing of skin scalds in a Bama miniature pig model.Firstly, the SCC was synthesized, and its chemical structure was characterized by FTIR and ~1H-NMR.Then the effect of the ratio of the SCC on the microstructure of t…
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Original research was done by HUANG Aibin,GUO Rui,XU Shaojun,MA Lie,GAO Changyou, Huang Aibin, Guo Rui, Xu Shaojun, Marxism-Leninism, Gao Changyou
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